Resistência antimicrobiana em biofilmes formados em dispositivos invasivos

Objective: to evaluate the microbiological profile and resistance patterns of biofilms on invasive devices recovered from Intensive Care Unit patients. Methods: a prospective cohort study of 157 adult patients in the immediate postoperative period. We analyzed 275 invasive devices collected under aseptic conditions and subjected to microbiological culture and susceptibility testing. Data were analyzed using Chi-square and Mann-Whitney tests. Results: biofilm formation occurred on the majority of devices, yielding 200 isolates, primarily Klebsiella pneumoniae (30%), Acinetobacter baumannii (25%), and Pseudomonas aeruginosa (20%). Multidrug-resistant (MDR) isolates accounted for 48% of the sample, while 19% were extensively drug-resistant (XDR) and 3% were pandrug-resistant (PDR). Central venous catheters showed a significantly higher rate of colonization by multidrug-resistant microorganisms (p