A review on Autologous Tooth-Derived Bone Grafts in Socket Preservation

Alveolar ridge preservation is crucial for maintaining bone volume and contour following tooth extraction to ensure successful implant placement. Conventional grafts such as allografts, xenografts, and alloplasts, though effective, have limitations including immunogenic risks, high cost, and incomplete remodeling. Autologous tooth-derived bone grafts (ATGs) have emerged as a sustainable and biocompatible alternative, utilizing the patient’s extracted tooth processed into a demineralized dentin matrix that closely mimics bone in structure and composition. Rich in collagen, hydroxyapatite, and intrinsic growth factors such as BMPs and TGF-β, ATGs demonstrate strong osteoconductive and osteoinductive potential. Clinically, they have shown effective socket preservation, rapid bone regeneration, and high implant success rates. Emerging innovations like nanotechnology-enhanced and stem cell–combined tooth grafts further expand their regenerative applications in endodontics and craniofacial reconstruction, marking a significant advancement in personalized bone regeneration.