Prevalence of Hepatitis B Associated Chronic Nephropathy in Baghdad, Iraq for the Year 2023

Background: The correlation between hepatitis B virus (HBV) and nephropathy presents a significant public health issue in Iraq. Aim: This study systematically investigates the association between hepatitis B surface antigen (HBsAg) serology and chronic kidney disease among residents of Baghdad, Iraq. Methods: We evaluated the clinical characteristics and serologic profiles of 609 patients with adult-onset HBV-related membranous nephropathy. Results: Individuals who are HBsAg (+) have a slightly increased risk of developing eGFR < 60 ml/min/1.73m2 or proteinuria compared to HBsAg (-) individuals. Conclusion: The study emphasizes the substantial impact of HBV on chronic kidney disease, independent of viral replication or inflammation. The findings underscore the importance of understanding the epidemiology and clinical implications of HBV infection in the context of renal complications, revealing potential immunological and pathological mechanisms. Further studies are recommended to elucidate the complex relationship between HBV infection and kidney impairment.