Clinical and health system factors associated with antiretroviral therapy adherence among people living with HIV and AIDS: cross-sectional survey insights from three ART facilities in Tamale, Ghana

ABSTRACT HIV and AIDS have attained a manageably chronic status as more infected people experience increases in their life quality and expectancy. Health system factors affect adherence to ART among persons living with HIV and AIDS(PLHIV). Nonetheless, literature on health-system factors and ART adherence among PLHIV is sparse. This study therefore, aimed to elucidate clinical and health system factors associated with antiretroviral therapy adherence among people living with HIV and AIDS in Tamale Metropolis. We conducted a facility-based cross-sectional survey of 418 PLHIV in the Tamale Metropolis, selected by consecutive sampling from three major antiretroviral therapy (ART) centres. Each factor associated with ART adherence, considered statistically significant at a p-value of