Esophagitis dissecans superficialis in an HIV patient with a history of substance abuse

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Authors: GF León Sanjuan, A García Martínez, MA Benavente Oyega
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Abstract

Abstract Esophagitis dissecans superficialis is a rare and often underdiagnosed entity, whose diagnosis relies on characteristic endoscopic findings. We present the case of a 58-year-old man with stage C3 human immunodeficiency virus (HIV) infection and a history of daily inhaled cannabis, cocaine, and heroin use. He was admitted with pneumococcal pneumonia, oropharyngeal candidiasis, and cachexia. Chest CT revealed thickening of the distal esophageal wall. Endoscopy demonstrated a circumferential desquamative and friable lesion consistent with superficial esophageal dissecans. Biopsies ruled out malignancy and viral infection. The compatible diagnosis was esophagitis dissecans superficialis, most likely secondary to chronic toxic substance use.

Fields of Study & Subjects

Potassium and Related Disorders Esophageal Cancer Research and Treatment Eosinophilic Esophagitis

Publication details

Journal / source
Revista Andaluza de Patología Digestiva
Volume
48
Issue
6
Pages
217–218
Publication date
7 January 2026
Language
EN