The main active ingredients of Smilacis Glabrae Rhizomaandthe clinical effect of preventing deep venous thrombosis of lower limbs after lumbar internal fixation

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Authors: Min Yi, Ting Zhang, Jianping Tong
Cited by: 0
References: 25

Abstract

Deep venous thrombosis (DVT) of the lower extremities is a common postoperative complication in patients with thoracolumbar fractures, with an increasing incidence rate year by year. Traditional Chinese medicine (TCM), especially Smilacis Glabrae Rhizoma, has shown unique advantages in preventing postoperative complications. The active components of Smilacis Glabrae Rhizoma have anti-inflammatory, analgesic, immune-regulating, and antioxidant effects. In this study, we observed the clinical effect of Smilacis Glabrae Rhizomain preventingDVT of the lower extremities after lumbar internal fixation (LIF). We found that the coagulation function indices and hemodynamics in the observation group were significantly improved compared with the control group. The incidence of DVT in the observation group was significantly lower (10.00%). The active component of Smilacis Glabrae Rhizoma, Quercetin, can accelerate blood flow, reduce blood stasis, and lower fibrinogen aggregation, effectively preventing DVT. Smilacis Glabrae Rhizomashows promise in reducing inflammation and promoting patient recovery

Fields of Study & Subjects

Traditional Chinese Medicine Clinical Research Traditional Chinese Medicine Analysis Venous Thromboembolism Diagnosis and Management

Publication details

Journal / source
Boletin Latinoamericano y del Caribe de plantas Medicinales y Aromaticas
Volume
25
Issue
1
Pages
14–25
Publication date
30 January 2026
Language
EN