The Use of Bedaquiline in Children from Foci of Drug-Resistant Tuberculosis Infection

Relevance . The increase in the incidence of drug-resistant tuberculosis necessitates the use of new etiotropic drugs. One of such contemporary drugs is bedaquiline. The literature on the safety and efficacy of bedaquiline in the treatment of tuberculosis in children of early and preschool age is limited. The aim of the study was to assess the tolerability and effectiveness of treatment regimens, including bedaquiline, in children of early and preschool age with active tuberculosis with drugresistant MBT sites. Clinical observation of 7 children of early and preschool age receiving bedaquiline included in the standard chemotherapy regimens for tuberculosis with drug-resistant pathogen sites. Results . Data were obtained on good tolerability and high clinical efficacy of bedaquiline included in standard chemotherapy regimens. Conclusion . It is advisable to continue the clinical use of bedaquiline in children of younger and preschool age.