Factors Influencing Drug-Resistant Tuberculosis Treatment Outcomes in Banda District of Bundelkhand Region, Uttar Pradesh.

Background: Tuberculosis (TB) is an infectious disease caused by the bacillus mycobacterium tuberculosis . Drug resistance Tuberculosis (DR-TB) is TB that is resistant to one or two first line drugs (WHO, 2023). It results from either primary infection with resistant bacteria or may develop in the course of a patient’s treatment .Different types of DR-TB are H.Mono,RR-TB,Pre-XDR and XDR. This study conducted with these Aim & Objectives: To determine factors influencing drug-resistant tuberculosis treatment outcomes in Banda district of Bundelkhand region. Material and Methods: This cross-sectional study explored the factors affecting treatment outcomes among drug-resistant tuberculosis (DR-TB) patients in Banda district. A total of 130 patients registered under the National Tuberculosis Elimination Program (NTEP) in Banda district of Bundelkhand region were included Results: Among the different types of TB, rifampicin-resistant TB (R.R. TB) was the most common, affecting 68.46% of patients, followed by MDR TB at 27.69%. Least common was H.mono accounting for 1.54%. Treatment outcomes vary significantly , with H.Mono cases achieving 100% success, while pre-XDR TB cases show a poor prognosis with 66.67 death rates and no cures. Conclusions: R.R. TB is the predominant form of drug-resistant TB, influenced by age, socioeconomic status, and addiction. Treatment outcomes are affected by adherence, stigma, and drug availability.