The Role Of Pancreatic Trypsin Inhibitor (Spink1) Gene Polymorphisms In The Course Of Acute Pancreatitis In The Uzbek Population

International Journal of Medical Science and Public Health Research 2026 Open access

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Authors: Madatov Kurbonboy Aminboevich, Ismailov Uktam Safaevich, Sharopov Asliddin Nasriddinovich, Matmuratov Seyilkhon Kuronboevich, Rakhimov Rasulbek Ibrokhimovich
DOI: 10.37547/ijmsphr/volume07issue02-07
Cited by: 0

Abstract

This article examines the results of the influence of the SPINK1 (Asn34Ser) polymorphism on the incidence of acute pancreatitis. Environmental factors, in conjunction with genetic factors, play a crucial role in the mechanism of acute pancreatitis development. It was found that there are ethnic differences in the distribution of allele and genotype frequencies of this gene's polymorphic variant. Further development of molecular genetic research through studying the genetic basis of pancreatitis is important for developing new methods of diagnosis and determining treatment strategies with an individualized approach to each patient.

Fields of Study & Subjects

Pancreatitis Pathology and Treatment Pancreatic and Hepatic Oncology Research Genetic Associations and Epidemiology

Publication details

Journal / source
International Journal of Medical Science and Public Health Research
Volume
7
Issue
2
Pages
46–50
Publication date
1 February 2026
Language
EN