Acute Toxicity and Antitoxic Effect of Compositions of Cytisine N-Alkyl (Aryl) Derivatives with Succinic Acid

The American Journal of Medical Sciences and Pharmaceutical Research 2026 Open access

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Authors: Latipova Shaxla Bekdurdiyevna, Азаматов Азизбек Азамат Угли, Турсунходжаева Фируза Муратовна, Aytmuratova Urkhiya Kallibekovna
DOI: 10.37547/tajmspr/volume08issue02-31
Cited by: 0

Abstract

In the article, the acute toxicity, resorptive effects, and antitoxic activity of N-alkyl (aryl) derivatives of cytisine and their compositions with succinic acid were studied in experimental animals using models of alcohol- and hypnotic-induced intoxication. The results demonstrated that these compositions possess relatively low acute toxicity and exhibit antitoxic effects under conditions of narcotic intoxication by reducing the duration of sleep.

Fields of Study & Subjects

Alkaloids: synthesis and pharmacology Forensic Toxicology and Drug Analysis Plant Toxicity and Pharmacological Properties

Publication details

Journal / source
The American Journal of Medical Sciences and Pharmaceutical Research
Volume
8
Issue
2
Pages
207–210
Publication date
1 February 2026
Language
EN