[Striatal dopamine transporter distribution pattern and its correlation with iron deposition in the substantia nigra pars compacta in Parkinson's disease based on 18F-FP-CIT PET-MRI].

PubMed 2026

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Authors: H M Lin, Y H Zhu, J Wang, Y H Yang, Jing-Jie Ge, P Wu, H W Zhang, F T Liu, Y H Guan, C T Zuo
DOI: 10.3760/cma.j.cn112137-20251212-03292
Cited by: 0

Abstract

At the time of clinical diagnosis, striatal DAT is already impaired and shows a negative correlation with SNc iron deposition, revealing a correlation between nigrostriatal pathway damage and DAT impairment in PD patients.

Fields of Study & Subjects

Parkinson's Disease Mechanisms and Treatments Neurological diseases and metabolism Neurological disorders and treatments

Publication details

Journal / source
PubMed
Volume
106
Issue
4
Pages
321–326
Publication date
27 January 2026
Language
ZH