[Risk factors and prognostic value of lymph node metastasis in patients undergoing curative resection for intrahepatic cholangiocarcinoma].

PubMed 2026

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Authors: P C Wei, Z M Y Chen, D L Ma, J L Hao, Zheng Luo, Y J Luo, L Y Qiao, Y Peng, Z L Kang, Qiang Cheng, J Gao, J Y Zhu
+1 more Z Li
DOI: 10.3760/cma.j.cn112139-20251124-00544
Cited by: 0

Abstract

Elevated carcinoembryonic antigen, preoperative lymphadenopathy, and large duct type histological subtype are independent risk factors for postoperative lymph node metastasis in ICC. Lymph node status significantly affects prognosis. Patients with lymph node-positive disease may benefit from retrieval of ≥6 lymph nodes and postoperative adjuvant therapy, whereas excessive lymphadenectomy should be avoided in lymph node-negative patients, in whom adjuvant therapy mainly contributes to delaying recurrence.

Fields of Study & Subjects

Cholangiocarcinoma and Gallbladder Cancer Studies Pediatric Hepatobiliary Diseases and Treatments Hepatocellular Carcinoma Treatment and Prognosis

Publication details

Journal / source
PubMed
Volume
64
Issue
4
Pages
349–359
Publication date
1 April 2026
Language
ZH