[Clinical characteristics of Pneumocystis jirovecii pneumonia in non-human immunodeficiency virus infected children].
Abstract
Non-HIV-infected children with PJP tend to occur in infants under 3 years old. It is often complicated by underlying diseases such as immunodeficiency, with most patients having a history of glucocorticoid or immunosuppressant use. Clinical manifestations and imaging findings lack specificity, and mNGS facilitates early diagnosis. The core treatment is trimethoprim-sulfamethoxazole, most children require respiratory support, and combination with low-dose glucocorticoids may improve prognosis.
Fields of Study & Subjects
Pneumocystis jirovecii pneumonia detection and treatment
Pneumonia and Respiratory Infections
Immunodeficiency and Autoimmune Disorders
Publication details
- Journal / source
- PubMed
- Volume
- 64
- Issue
- 2
- Pages
- 204–209
- Publication date
- 2 February 2026
- Language
- ZH