[Granulomatosis with polyangiitis involving the sinonasal region: a clinicopathological analysis of 22 cases].
Abstract
Sinonasal GPA primarily occurs in young and middleaged adults, typically presenting with nonspecific clinical symptoms. Its characteristic pathological findings include necrotizing granulomas and vasculitis. However, in most cases, only small biopsy specimens are available for histopathological evaluation, making it challenging to identify all diagnostic features microscopically. Therefore, a definitive diagnosis should be made by comprehensively evaluating clinical manifestations, radiological findings, histopathological characteristics, and serological testing.
Publication details
- Journal / source
- PubMed
- Volume
- 55
- Issue
- 1
- Pages
- 22–27
- Publication date
- 8 January 2026
- Language
- ZH