[Polymorphous low-grade neuroepithelial tumor of the young: a molecular pathological study].

PubMed 2026

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Authors: Q Qin, L A Guo, Tao Luo, D D Wang, L Chen, L H Teng, D H Lu, X H Yao, Y S Piao
DOI: 10.3760/cma.j.cn112151-20250729-00517
Cited by: 0

Abstract

PLNTY usually occurs in adolescents and is associated with epilepsy. Its diagnosis necessitates a combination of clinical, histopathological, and molecular genetic alterations. In molecular level, PLNTY exhibits alterations in the MAPK pathway; while its DNA methylation profile demonstrates diversity. Most patients achieved seizure-free outcomes postoperatively, indicating a favorable prognosis.

Publication details

Journal / source
PubMed
Volume
55
Issue
1
Pages
51–57
Publication date
8 January 2026
Language
ZH