[Adenovirus-induced liver failure in adults following allogeneic hematopoietic stem cell transplantation: a report of two cases and literature review].

PubMed 2026 Open access

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Authors: X J Wang, N Wang, Y Yang, Yang Cao, F K Meng, Y C Zhang, J H Xu
DOI: 10.3760/cma.j.cn121090-20250804-00361
Cited by: 0

Abstract

Human adenovirus (HAdV) hepatitis is a rare but rapidly progressive and often fatal complication following allogeneic hematopoietic stem cell transplantation. The present study reported the management of two patients with lymphoproliferative disease who developed HAdV infection after haploidentical hematopoietic stem cell transplantation and subsequently died of liver failure. These cases highlight the importance of early multi-site screening, dynamic monitoring, and timely intervention for HAdV in high-risk patients to reduce mortality risk and improve prognosis.

Fields of Study & Subjects

Hematopoietic Stem Cell Transplantation Cytomegalovirus and herpesvirus research Viral-associated cancers and disorders

Publication details

Journal / source
PubMed
Volume
47
Issue
1
Pages
79–82
Publication date
14 January 2026
Language
ZH