[A case of toxic shock syndrome secondary to severe bone marrow suppression induced by azathioprine in a patient with autoimmune hepatitis].

PubMed 2026 Open access

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Authors: Yuanyuan Ren, M Kong, C Y Huang, X Q Bian, H X Liu, D L Mou, Y Chen
DOI: 10.3760/cma.j.cn501113-20250508-00180
Cited by: 0

Abstract

1例自身免疫性肝炎患者硫唑嘌呤治疗后出现严重骨髓抑制、进而继发金黄色葡萄球菌感染、引发中毒性休克综合征（TSS），临床表现为休克伴多器官功能不全，包括急性肾损伤、心肌损害、皮肤软组织感染、肺部感染。通过积极的抗感染、器官支持治疗以及外科清创干预，患者病情逐步改善并出院。突出反映了多学科诊疗在免疫抑制剂应用等复杂病例管理中的价值。 Keywords: 自身免疫性肝炎, 中毒性休克综合征, 金黄色葡萄球菌感染, 多器官功能障碍综合征, NUDT15基因, 诊断, 治疗

Fields of Study & Subjects

Sepsis Diagnosis and Treatment Antimicrobial Resistance in Staphylococcus Drug-Induced Hepatotoxicity and Protection

Publication details

Journal / source
PubMed
Volume
34
Issue
1
Pages
99–102
Publication date
20 January 2026
Language
ZH