Ruptured Sinus of Valsalva Aneurysm in a Patient with Mixed Connective Tissue Disease: Case Report
Abstract
Sinus of Valsalva aneurysm is a rare cardiac anomaly, affecting approximately 0.09 % of the population. Its rupture represents a life-threatening event that can rapidly lead to heart failure. We report a 32-year-old woman with mixed connective tissue disease presenting with right-sided heart failure. Echocardiography demonstrated a ruptured right coronary cusp sinus of valsalva aneurysm into the right ventricle with moderate aortic regurgitation. Surgical repair was successfully performed, and histopathology supported an autoimmune-mediated etiology. To our knowledge, this is the first reported case of ruptured sinus of valsalva aneurysm occurring in a patient with autoimmune mixed connective tissue disease.
Fields of Study & Subjects
Aortic Disease and Treatment Approaches
Coronary Artery Anomalies
Cardiac Structural Anomalies and Repair
Publication details
- Journal / source
- Journal of the Saudi Heart Association
- Volume
- 38
- Issue
- 1
- Pages
- 3–3
- Publication date
- 15 February 2026
- Language
- EN