Establishing a Mouse Model of Vaginal Group B Streptococcus Infection

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Abstract

Source: Patras, K. A., Doran, K. S. A Murine Model of Group B Streptococcus Vaginal Colonization. J. Vis. Exp. (2016)This video demonstrates the preparation and vaginal inoculation of a hormone-treated female mouse with Group B Streptococcus to model infection. It explains how to culture and prepare the bacteria, administer the inoculum into the vaginal lumen, and ensure successful infection.

Fields of Study & Subjects

Neonatal and Maternal Infections Reproductive tract infections research Streptococcal Infections and Treatments

Publication details

Journal / source
Journal of Visualized Experiments
Publication date
27 February 2026
Language
EN