Establishing Bacterial–Fungal Cross-Kingdom Biofilms for Studying Oral Pathogenesis
Abstract
Source: Schlafer, S, and Frost Kristensen, M. Monitoring Extracellular pH in Cross-Kingdom Biofilms using Confocal Microscopy. J. Vis. Exp. (2020)This video demonstrates the cultivation of Streptococcus mutans and Candida albicans cross-kingdom biofilms under oral-like conditions to model bacterial–fungal interactions, enabling the study of microbial synergy, glucan-mediated adhesion, and acidogenic virulence in oral pathogenesis.
Fields of Study & Subjects
Oral microbiology and periodontitis research
Bacterial biofilms and quorum sensing
Antifungal resistance and susceptibility
Publication details
- Journal / source
- Journal of Visualized Experiments
- Publication date
- 27 February 2026
- Language
- EN