Investigation of a Blue Light LED Device to Suppress Wound Pathogens Using a Collagen-Based Synthetic Skin Model

), caused no detectable chemical or conformational degradation of the collagen matrix, unlike the damaging effects observed with germicidal UV-C control. Finally, a unique evaluation in an aerosol chamber demonstrated that BL treatment reduced microbial deposition on surfaces by over 95%, highlighting its potential for mitigating nosocomial infections. These findings demonstrate the suitability of skin-mimicking substrates as an accessible alternative for evaluating BL in preclinical testing, thereby eliminating the need for animal models.