Clinicopathological predictors of mortality and recurrence after gastrectomy in elderly patients

Aims: Gastric cancer remains one of the leading causes of cancer-related deaths worldwide. A significant proportion of patients are elderly, a group with unique challenges including higher comorbidity burden and reduced treatment tolerance, making the identification of prognostic determinants essential for personalized care. To evaluate clinicopathological factors associated with mortality and recurrence in gastric cancer patients aged 65 years and older undergoing gastrectomy at a tertiary referral center. Methods: This retrospective cohort study included 65 patients aged ≥65 years who underwent total or subtotal gastrectomy at a tertiary care center. Demographic, surgical, pathological, and treatment data were analyzed. Associations with mortality and recurrence were assessed using Chi-square and Mann-Whitney U tests, with statistical significance defined as p