An in Vitro Investigation for Comparative Assessment of Triple Antibiotic Paste, Nitrofurantoin and Neopex on Bond Strength of Sealer

Aim: To compare and evaluate the effect of Nitrofurantoin, Triple Antibiotic Paste and Oil based Calcium hydroxide on the push-out bond strength of MTA based sealer.  Material and Methods: The study included sixty (60) mature, single-rooted mandibular teeth that had been recently extracted. Calculus, debris, and soft tissue remains were extracted from the teeth using an ultrasonic scaler. F3 Protaper rotary instruments were used to instrument each sample. After the specimens were instrumented, Based on the location of the intracanal medicament, specimens were split into three experimental groups at random.: Group 1: Triple Antibiotic Paste (TAP), Group 2: Nitrofurantoin (NIT), and Group 3: Oil-based Calcium Hydroxide (n = 20). MTA fillapex was used for obturation following the removal of intracanal medication. A universal testing machine was used to determine the push out bond strength.  Results: Compared to the nitrofurantoin group, the triple antibiotic paste group produced even greater bond. When compared to the other test groups, the Neopex group's bond strength was significantly weakened.  Conclusion: It may be inferred that Triple Antibiotic Paste, Nitrofurantoin, and oil based calcium hydroxide significantly increased the bonding capacity of resin-based sealer. There are notable differences between Triple Antibiotic Paste, Nitrofurantoin, and oil based calcium hydroxide mean push out bond strength levels.