Mobile Health, Pharmacist-Led Interventions and Home Medication Management: A Comprehensive Review of the Literature

Medication adherence remains a central determinant of treatment success in chronic diseases. In recent years, the integration of pharmacist-led services, home-based reviews and mobile health (mHealth) technologies has gained increasing attention as innovative mechanisms to improve adherence, quality of life (QOL) and clinical outcomes. This review synthesizes evidence from 17 studies spanning pharmacist interventions, mHealth applications, home medication reviews, telehealth strategies and caregiver-oriented digital learning. The findings show consistent short-term improvements in adherence and patient engagement across many digital and pharmacist-driven programs, however evidence on long-term clinical effectiveness, scalability and sustainability remains limited. Substantial gaps persist around user engagement, privacy concerns, contextual adaptability and healthcare provider integration. The review highlights the need for large, theory-driven and community-based trials to validate and optimize these evolving models of care.