Trends in Acute Coronary Syndromes in Systemic Lupus Erythematosus: Are We Moving in the Right Direction?

The Journal of Rheumatology 2026 Open access

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Authors: Susan Manzi
DOI: 10.3899/jrheum.2026-0067
Cited by: 0

Abstract

Cardiovascular (CV) disease (CVD) in systemic lupus erythematosus (SLE) is driven by chronic inflammation, traditional risk factors, and SLE-specific immunological processes that likely begin before clinical diagnosis. Multiple study designs, including population-based registries, case-control studies, and systematic reviews and metaanalyses, consistently show a 2- to 3-fold increased risk of CVD in patients with SLE.1-4

Fields of Study & Subjects

Systemic Lupus Erythematosus Research Acute Myocardial Infarction Research Systemic Sclerosis and Related Diseases

Publication details

Journal / source
The Journal of Rheumatology
Volume
53
Issue
4
Pages
356–357
Publication date
15 February 2026
Language
EN