Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?

Cleveland Clinic Journal of Medicine 2026 Open access

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Authors: Dylan T. Timberlake, Sushmitha Boppana, James Fernandez
DOI: 10.3949/ccjm.93a.25026
Cited by: 0

Abstract

Because reactions to intravenous infusions of radiocontrast media, monoclonal antibodies, or chemotherapy agents can be severe and life-threatening, researchers have tried to decrease their rate and severity by giving antihistamines, corticosteroids, or both before the infusions. This review summarizes the information about corticosteroid pretreatment to prevent infusion-related reactions, to help clinicians determine which patients may benefit from it.

Fields of Study & Subjects

Acute Kidney Injury Research Hepatocellular Carcinoma Treatment and Prognosis Chemotherapy-related skin toxicity

Publication details

Journal / source
Cleveland Clinic Journal of Medicine
Volume
93
Issue
1
Pages
47–53
Publication date
1 January 2026
Language
EN