PCDHGB7 Methylation Characteristics and Their Clinical Significance in Lung Adenocarcinoma Based on the TCGA Database
Abstract
ObjectiveThis study used The Cancer Genome Atlas (TCGA) database to investigate the methylation levels of PCDHGB7 in lung adenocarcinoma tissues and analyze its association with clinical pathological features of lung adenocarcinoma, and its prognostic predictive value. MethodsMethylation data of PCDHGB7 from 473 lung adenocarcinoma tissues and 32 normal tissues in the TCGA database were derived and analyzed to assess between-group variance and determine the correlation of methylation levels with clinical pathological features and overall survival. ResultsPCDHGB7 exhibited significantly higher methylation levels in lung adenocarcinoma tissues than in normal tissues (P
Fields of Study & Subjects
Epigenetics and DNA Methylation
Cancer-related molecular mechanisms research
Lung Cancer Research Studies
Publication details
- Journal / source
- DOAJ (DOAJ: Directory of Open Access Journals)
- Publication date
- 1 February 2026
- Language
- ZH