Effect of Induced Hypertension Therapy According to the Mechanism of Single Subcortical Infarction
Abstract
Background and Purpose Induced hypertension therapy (IHT) is effective for treating early neurological deterioration (END) in patients with single subcortical infarction (SSI).However, the underlying pathophysiology of SSI is diverse and may affect the efficacy of IHT. MethodsWe reviewed patients with SSI who experienced END and received IHT were enrolled.END was defined as ≥2-point increase in the National Institutes of Health Stroke Scale (NIHSS) score, ≥1 motor point increase.IHT was performed by using phenylephrine infusion to raise systolic blood pressure by 10%-20% over baseline.SSI was classified into three subtypes: distal (dSSI), proximal (pSSI), and SSI with parental artery disease (SSIPAD; with stenosis at parental artery disease
Fields of Study & Subjects
Acute Ischemic Stroke Management
Intracerebral and Subarachnoid Hemorrhage Research
Intracranial Aneurysms: Treatment and Complications
Publication details
- Journal / source
- Journal of Clinical Neurology
- Volume
- 22
- Issue
- 2
- Pages
- 153–153
- Publication date
- 1 January 2026
- Language
- EN