Skin Microbiome Profiling in Patients with Primary Sjögren Disease Compared to Healthy Individuals

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Authors: Sujin Jo, Hoonhee Seo, Kyung‐Ann Lee, Sukyung Kim, Md Abdur Rahim, Tapan Indrajeet Barman, H K Kim, Hui Song
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Abstract

and a marked reduction in microbial diversity in SjD patients. Beta diversity analyses revealed distinct clustering among groups. Functional prediction suggested the downregulation of metabolic pathways associated with microbial homeostasis. Our findings propose that alterations in the skin microbiota may contribute to SjD pathogenesis and serve as potential biomarkers or therapeutic targets.

Fields of Study & Subjects

Dermatology and Skin Diseases Salivary Gland Disorders and Functions Gut microbiota and health

Publication details

Journal / source
Journal of Microbiology and Biotechnology
Volume
36
Pages
e2510010–e2510010
Publication date
11 February 2026
Language
EN