Skin Health Function of Distilled Soju Byproduct Fermented with Saccharomyces cerevisiae MGE 3400

related HAS2 expression, UV-protective effects, and wound-healing properties using the HaCaT cell line.S. cerevisiae MGE 3400 fermented distilled soju byproduct showed stronger antioxidant and antimicrobial activities than the control.In addition, they promoted the expression of hyaluronan synthase 2 (HAS2) and insulin-like growth factor 1 (IGF-1) genes, enhanced ultraviolet (UV) damage protection, and accelerated wound closure in keratinocyte HaCaT cells, suggesting an overall improvement in skinregenerative potential.These findings suggest that S. cerevisiae MGE 3400 can enhance the functional properties of distilled soju byproduct, supporting their use as a sustainable source of natural ingredients for cosmetic and dermatological applications.