Propionibacterium freudenreichii MJ2 Improves Dexamethasone-Induced Muscle Atrophy in Rats by Increasing Muscle Mass and Muscle Fiber Area
Abstract
) in DEX-treated C2C12 cells while activating proteins (p-Akt/Akt and p-mTOR/mTOR) associated with muscle protein synthesis. Live- and HK-MJ2 treatment increased grip strength, muscle mass, and muscle fiber area in rats with DEX-induced muscle atrophy. In conclusion, both live- and HK-MJ2 increase muscle mass and muscle fiber area, resulting in the improvement of DEX-induced muscle atrophy.
Fields of Study & Subjects
Muscle Physiology and Disorders
Probiotics and Fermented Foods
Muscle metabolism and nutrition
Publication details
- Journal / source
- Journal of Microbiology and Biotechnology
- Volume
- 36
- Pages
- e2510050–e2510050
- Publication date
- 18 January 2026
- Language
- EN