Integrated Metabolomics and Microbial Profiling in Patients with Irritable Bowel Syndrome

Journal of Microbiology and Biotechnology 2026 Open access

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Authors: Y. J. Kim, Mee-Hyun Lee, Seung-Ho Seo, Juhan Pak, Soobin Bae, Gayoun Lee, Gi Dae Kim, Hyun Sik Kim, Young-ho Moon, Hong-Seok Son
DOI: 10.4014/jmb.2511.11041
Cited by: 1
References: 47

Abstract

. This study demonstrated that integrating the three datasets-plasma metabolites, urinary metabolites, and gut microbial communities-provides a comprehensive overview of IBS pathophysiology. Together, these findings indicate that functional interactions between discriminative gut microbial features and systemic metabolic alterations, particularly within fatty acid metabolism, may represent a mechanistic link between gut dysbiosis and the metabolic manifestations of IBS.

Fields of Study & Subjects

Gut microbiota and health Metabolomics and Mass Spectrometry Studies Gastrointestinal motility and disorders

Publication details

Journal / source
Journal of Microbiology and Biotechnology
Publisher
Korean Society for Microbiology and Biotechnology
Volume
36
Pages
e2511041–e2511041
Publication date
22 January 2026
Language
EN