Evaluating VGG16, ResNet50, and Xception for COVID-19 Detection via a Web-Based Deep Learning Interface
Abstract
The global outbreak of COVID-19 has emphasized the need for fast and accurate diagnostic methods, especially in areas where advanced testing facilities are scarce or unavailable. This research proposes a deep learning-based method for the binary classification of chest X-ray images aimed at detecting COVID-19 infections. We evaluate and compare the performance of three prominent Convolutional Neural Network (CNN) architectures ResNet50, VGG16, and Xception trained on publicly available chest radiograph datasets. Additionally, a confusion matrix, training versus validation accuracy plots, and the ROC curve are employed to gain deeper insights into the model's effectiveness and diagnostic capability. To enhance usability, a user-friendly web interface has also been developed, enabling users to upload images and obtain real-time classification results. Experimental findings indicate that all three models perform well in distinguishing COVID-19 cases, with the Xception model achieving the highest accuracy.
Fields of Study & Subjects
COVID-19 diagnosis using AI
Domain Adaptation and Few-Shot Learning
Face recognition and analysis
Publication details
- Journal / source
- Advances in computational intelligence and robotics book series
- Pages
- 167–192
- Publication date
- 9 January 2026
- Document type
- Book chapter