Genome Editing Technologies in Precision Medicine

Recent developments in genome editing technologies have revolutionized the field of genome precision medicine, offering unprecedented opportunities for genetic flaw correction, disease manipulation, and personalized treatment plans. These technologies include CRISPR-Cas systems, base editing, and prime editing, which can revolutionize treatments for monogenic disorders, cancers, and multifactorial complex diseases. However, challenges such as delivery bottlenecks, reactions, unintentional genetic changes, and ethical issues remain. The chapter emphasizes the need for improved viral and non-viral vectors, specificity tests, and efficient regulatory methods. It also addresses socioeconomic and accessibility concerns for equitable access to genome editing treatments. The chapter aims to balance innovation and responsible translation, considering both preclinical and clinical advances and current issues in genome editing in precision medicine.