Exploring LEPR -Linked Metabolic Diversity through Gut Microbiome-Metabolome Network Analysis in Non-Obese Adults

Biomolecules & Therapeutics 2026 Open access

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Authors: Kyeong-Seog Kim, Joo‐Youn Cho, Ye Chan Park, J. Hong, Jin-Gyu Jung, Jung Sunwoo
DOI: 10.4062/biomolther.2025.161
Cited by: 0

Abstract

genetic variation is associated with distinct serum metabolomic patterns and microbiome-host networks in healthy adults. Although no direct leptin signaling links were found, network-level associations suggest indirect genetic influences on metabolic states through microbiome-metabolome interactions. These findings advance understanding of personalized metabolic regulation and gene-microbiome interplay.

Fields of Study & Subjects

Gut microbiota and health Nutrition Genetics and Disease Metabolomics and Mass Spectrometry Studies

Publication details

Journal / source
Biomolecules & Therapeutics
Volume
34
Issue
2
Pages
448–460
Publication date
27 February 2026
Language
EN