Aβ₁₋₄₀ Enhances Platelet Sensitivity to Thrombin via NADPH Oxidase–ROS Signaling and Integrin α IIb β ₃ Engagement
Abstract
axis that drives platelet hyperactivation and cerebrovascular interactions in AD. Targeting this pathway with antithrombotic or antioxidative strategies may offer therapeutic potential in mitigating AD-associated vascular pathology.
Fields of Study & Subjects
Platelet Disorders and Treatments
Neutrophil
Myeloperoxidase and Oxidative Mechanisms
Cell Adhesion Molecules Research
Publication details
- Journal / source
- Biomolecules & Therapeutics
- Publisher
- The Korean Society of Applied Pharmacology
- Volume
- 34
- Issue
- 2
- Pages
- 365–378
- Publication date
- 27 February 2026
- Language
- EN