Diffuse lipomatosis of the thyroid and thyroid papillary carcinoma, lipomatous type: A case report

ABSTRACT: Diffuse lipomatosis, characterized by the widespread presence of mature adipose tissue within the thyroid, is a rare condition. The presence of adipose tissue may vary within the neoplastic nodules in cases of diffuselipomatosis. Although the etiology remains unclear, it is generally regarded as an embryological developmental anomaly. This case report presents a 68-year-old female patient presented to the Ear, Nose, and Throat (ENT) clinic with complaints of neck swelling. Ultrasonographic examination revealed an enlarged thyroid gland and a 2 cm nodule. The patient subsequently underwent the left lobectomy. Histological examination of the thyroid tissue showed diffuse lipomatosis and thyroid papillary carcinoma with adipose tissue in the stroma. In pathology practice, the presence of adipose tissue in the thyroid is a rare finding that can occur in both benign and malignant neoplasms.