Double Jeopardy at the Neuromuscular Junction: Guillain–Barré Syndrome Overlapping with Myasthenia Gravis Challenges in Rehabilitation and Recovery

Indian Journal of Physical Medicine and Rehabilitation 2026 Open access

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Authors: T K Abins, Ravi Gaur, Nitesh Manohar Gonnade, Nagma Sheenam, Veluguleti Ujwal, Arindam Ghosh, Megha Sunil
DOI: 10.4103/ijpmr.ijpmr_61_25
Cited by: 0
References: 7

Abstract

Abstract Guillain–Barré syndrome (GBS) and myasthenia gravis (MG) are distinct autoimmune neuromuscular disorders, but rare overlap can occur. Such coexistence complicates diagnosis, prolongs intensive care stay and challenges rehabilitation due to dual respiratory, bulbar and motor involvement. We report a patient initially diagnosed with GBS, later found to have overlapping MG, who underwent structured multidisciplinary rehabilitation. The case highlights the importance of individualised rehabilitation planning, vigilant respiratory management and structured follow-up in improving the outcomes.

Fields of Study & Subjects

Peripheral Neuropathies and Disorders Myasthenia Gravis and Thymoma Medical Practices and Rehabilitation

Publication details

Journal / source
Indian Journal of Physical Medicine and Rehabilitation
Volume
36
Issue
2
Pages
165–168
Publication date
30 January 2026
Language
EN