Oncologic emergencies

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Authors: Indira Jayakumar, Rhea John, Milind Ballal
Cited by: 0
References: 13

Abstract

Oncologic emergencies in pediatric patients are acute, potentially life-threatening complications that can arise from the malignancy itself or its treatment. Structural emergencies such as spinal cord compression and tumor rupture require urgent surgical or interventional management. Metabolic and hematologic emergencies, including tumor lysis syndrome, hypercalcemia, and disseminated intravascular coagulation, demand rapid stabilization. Chemotherapy-related toxicities, particularly from agents such as anthracyclines, methotrexate, asparaginase, and ifosfamide, necessitate vigilant monitoring, early detection, and supportive care to mitigate complications. Multidisciplinary care is essential for optimal outcomes. Awareness and early intervention in pediatric oncologic emergencies are paramount. A structured approach incorporating timely recognition, stabilization, and targeted therapy improves survival and reduces morbidity in this vulnerable population.

Fields of Study & Subjects

Methemoglobinemia and Tumor Lysis Syndrome Acute Lymphoblastic Leukemia research Neutropenia and Cancer Infections

Publication details

Journal / source
JOURNAL OF PEDIATRIC CRITICAL CARE
Volume
13
Issue
1
Pages
50–55
Publication date
1 January 2026
Language
EN