The Effect of Smokıng on Serum Immunoglobulın Levels in Türkiye: A Cross-Sectıonal Study

BACKGROUND: The numerous toxic substances present in cigarettes have a suppressive effect on the immune system, lowering antibody levels and making smokers more susceptible to diseases. AIM: To determine the effect of smoking on serum IgG, IgA, IgM, and IgE levels in those who smoke in Türkiye. METHODS: This cross-sectional study was conducted over a 3-month period in individuals who visited the Family Medicine Outpatient Clinic. Those who smoked cigarettes were included as the case group, and non-smokers as the control group. The nicotine dependence levels of the smokers were recorded using the Fagerström Nicotine Dependence Test (FNBT). IgG, IgA, IgM, and IgE levels were measured in both groups. Comparisons were made between the two groups, and a significant P value was taken as