Successful management of malignant hyperthermia with dantrolene complicated by upper limb DVT: A case report
Abstract
Malignant hyperthermia (MH) remains the monster every anesthesiologist can meet suddenly in the OR. It is a rare but life-threatening hypermetabolic reaction triggered by certain anesthetic agents. Here we present a case of a 40-year-old male, who developed MH 45 min after induction of anesthesia for functional endoscopic sinus surgery (FESS) in King Abdulaziz Medical City in KSA. It was not the first time the patient was exposed to general anesthesia, with no relevant family history. Early recognition, prompt administration of dantrolene, and aggressive supportive measures resulted in full recovery. Despite the full recovery from metabolic derangements, he developed upper extremity DVT in the same limb dantrolene was administered.
Fields of Study & Subjects
Ion channel regulation and function
Electroconvulsive Therapy Studies
Anesthesia and Sedative Agents
Publication details
- Journal / source
- Saudi Journal of Anaesthesia
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 20
- Issue
- 1
- Pages
- 217–219
- Publication date
- 1 January 2026
- Language
- EN