Serum adipocyte fatty acid-binding protein is associated with impaired endothelial function in nondialysis chronic kidney disease

Tzu Chi Medical Journal 2026 Open access

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Authors: Teoh Ling Lun, Yu-Li Lin, Chih‐Hsien Wang, Yu‐Hsien Lai, Chiu‐Huang Kuo, Chi-Chong Tang, Bang‐Gee Hsu
DOI: 10.4103/tcmj.tcmj_173_25
Cited by: 0
References: 26

Abstract

A BSTRACT Objectives: Adipocyte fatty acid-binding protein (A-FABP) has been implicated in atherosclerosis, and endothelial dysfunction is a critical contributor to cardiovascular outcomes in chronic kidney disease (CKD). This study evaluated links between serum A-FABP and endothelial function among patients with CKD who were not on dialysis. Materials and Methods: Fasting serum from 151 adults with CKD not on dialysis was analyzed for A-FABP using enzyme immunoassay. Endothelial function was measured noninvasively through digital thermal monitoring (DTM), yielding vascular reactivity index (VRI) scores categorized as poor (

Fields of Study & Subjects

Cardiovascular Disease and Adiposity Adipokines Inflammation and Metabolic Diseases Chronic Kidney Disease and Diabetes

Publication details

Journal / source
Tzu Chi Medical Journal
Volume
38
Issue
2
Pages
203–209
Publication date
12 January 2026
Language
EN