Data underlying the publication: Verification of a Fluid-Structure Interaction model for aortic stenosis through comparison with in vitro experiments

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Authors: Sabine Verstraeten, Roel Meiburg, Koen Janssens, Martijn Hoeijmakers, Nils Karajan, Marcel C. M. Rutten, Marcel Van 't Veer, Pim A.L. Tonino, Frans N. van de Vosse, Wouter Huberts
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Abstract

This dataset supports a manuscript that verifies a patient-specific Fluid-Structure Interaction (FSI) model of aortic stenosis against in vitro experiments. The in vitro experiments include a mock-loop circulatory system with rubber valve models derived from patient CT images, both with and without calcifications. Experiments were conducted under varying flow conditions simulating rest and exercise, based on clinical measurements during dobutamine stress testing, with dobutamine infusion rates of 0, 5, 10, and 20 microg/kg/min. During the experiments pressures were measured proximally and distally to the rubber valve with 10EZ pressure sensors. Flow was measured distally to the valve using an ultrasonic flow probe. Valve movement was recorded with an endoscope connected to a camera. The experiment was replicated in the FSI model, implemented in LS-DYNA R16. Flow and valve dynamics of the in vitro experiments and the FSI model were compared. This data set contains:1) Matlab scripts to reproduce figures of manuscript.2) Post-processed simulation and experimental data needed to reproduce figures of manuscript.3) LS-DYNA input files for the simulations (.k files).

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Aortic Disease and Treatment Approaches Elasticity and Material Modeling

Publication details

Journal / source
4TU.ResearchData
Publication date
16 January 2026
Language
EN
Document type
Dataset