The Effects of Fytomax Women Antioxidant Supplements on Blastulation Rate

Embryo blastulation is a pivotal stage occurring during embryonic development. Blastulation can be affected by oxidative stresses, such as reactive oxygen species, that may damage embryo development. This study aimed at comparing the blastulation rate obtained from sub-fertile women, under antioxidant supplementation (Fytomax Women, KSMC Laboratory, PTY, LTD Belgium; http://www.ksmc.eu/), residing in Gabon, to the blastulation rate obtained through a systematic review and a meta-analysis of the literature search. Statistical analysis was performed using the MedCalc® statistical software. The main result of this study indicated a significantly (p = 0.015) higher blastulation rate in sub-fertile women under antioxidant supplement compared to the blastulation rate from the systematic review (68.00 ± 23 vs 50.04 ± 13). This current cohort study supports previous evidence suggesting that the antioxidant supplement, such as Fytomax Women, can improve selected reproductive outcomes in women undergoing ART.