Analysis of Risk Factors in Patients with Cerebrovascular Disease Complicated by Chronic Coronary Syndrome

Background: The number of patients with both cerebrovascular disease and chronic coronary syndrome (CCS) is rising, but shared risk factors are not well understood. This study identifies key risk factors by analyzing clinical data from these patients. Methods: We analyzed 403 patients (203 with intracranial aneurysms, 200 with intracranial stenosis) treated at the Second Affiliated Hospital of Kunming Medical University from June 1, 2022, to July 31, 2024. Data on demographics, medical history, and lab results were collected. Univariate and binary logistic regression analyses were used to identify significant risk factors. Results: Patients with intracranial stenosis and CCS were mostly male and had higher rates of diabetes, hyperhomocysteinemia, elevated NLR, troponin, and BNP. Those with aneurysms and CCS were also predominantly male and showed associations with older age, hypertension, diabetes, alcohol use, aneurysm rupture, and elevated uric acid, lipoprotein(a), homocysteine, and troponin. Logistic regression confirmed that male sex, older age, diabetes, and hyperlipoproteinemia. were independently linked to dual disease. Conclusion: Patients with both cerebrovascular disease and CCS are more likely to be male, older, and have diabetes or hyperlipidemia. These findings support routine cardiovascular risk assessment in this group.