Advances in Total-Body PET/CT Research

With the iterative advancement of PET/CT technology, uEXPLORER, the first ultra-long axial field-of-view (LAFOV) PET/CT system enabling single-bed-position whole-body imaging has entered clinical use. This scanner significantly enhances molecular imaging performance through ultra-fast scanning, low-dose imaging, whole-body dynamic imaging, and simultaneous multi-tracer imaging capabilities. Recently, we have witnessed rapid growth in related research, which primarily focused on single imaging protocol optimization and clinical application exploration. This article systematically reviews current studies on uEXPLORER, aiming to inform future research directions.