Anterior Cruciate Ligament: Injury Etiology, Molecular Structure, Postoperative Rehabilitation, and Evidence-Based Insights

Journal of Biosciences and Medicines 2026 Open access

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Authors: Yanxiang Lu, Su Luo, Qiuxia Huang, Yining Lu, Qiufen Zhang, Haidong Zhou, Lizhu Lu, Junxiu Zhou, Xuanfei Su, Erxi Xu, Yifang Luo
DOI: 10.4236/jbm.2026.142028
Cited by: 0
References: 27

Abstract

The anterior cruciate ligament (ACL) is a critical stabilizer of the knee joint, and its injury is highly prevalent in sports and daily activities, often leading to long-term joint dysfunction and osteoarthritis (OA) if not managed properly. This review synthesizes evidence from 25 key studies to systematically explore the injury causes of the ACL, its molecular structural characteristics, and evidence-based postoperative rehabilitation protocols. By integrating findings from basic science, clinical trials, and cohort studies, this review aims to provide a comprehensive reference for orthopedic surgeons, sports medicine specialists, and rehabilitation clinicians in the diagnosis, treatment, and rehabilitation management of ACL injuries.

Fields of Study & Subjects

Knee injuries and reconstruction techniques Tendon Structure and Treatment Sports injuries and prevention

Publication details

Journal / source
Journal of Biosciences and Medicines
Volume
14
Issue
02
Pages
383–394
Publication date
1 January 2026
Language
EN