Risk Factors for Acquiring Multidrug Resistant Microorganisms (MDROs) in Hospital Settings: A Retrospective Study in a Reference Center

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Authors: Volatiana Andriananja, Eldinaud Botofotsy, Vatsiarizandry Mandrosovololona, Laza Randremasinjara, Mamy Jean de Dieu Randria, Rado Lazasoa Andrianasolo
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Abstract

Multidrug-resistant microrganisms (MDROs) infections are a major challenge in hospitals.MDROs affect developed and developing countries and even intensive care and non-intensive care units.In this context, we conducted a study which aims to identify the factors leading to the acquisition of MDROs in a nonintensive care unit.Our study was a retrospective and analytical study.The frequency of diabetes was 64%.The factors leading to the acquisition of MDROs were: invasive medical care (P < 0.001); the presence of MDROs of a urinary catheter and nosocomial infections increased the risk of MDROs infection by six and nine times, respectively (OR 6.2 [95% CI: 2.1 -17.9] and P < 0.001; OR 9.1 [95% CI: 3.2 -25.2] and P < 0.001).MDROs are still common in patients with diabetes; infection prevention and control measures and antimicrobial stewardship programmes need to be implemented to better address the problem.

Fields of Study & Subjects

Infection Control in Healthcare Nosocomial Infections in ICU Antibiotic Resistance in Bacteria

Publication details

Journal / source
OALib
Volume
13
Issue
01
Pages
1–11
Publication date
1 January 2026