Inflammatory Myofibroblastic Tumour of the Colon in a Child: A Case Report and Literature Review
Abstract
In the World Health Organization (WHO) classification, inflammatory myofibroblastic tumor is categorized among intermediate neoplasms and can affect various organs such as the lungs, pancreas, bladder, and uterus, while its colonic localization is rare. We present the case of a 4-year-old girl with a history of chronic constipation. Clinical examination revealed the presence of a firm and mobile mass measuring 5 cm in the right hypochondrium. Abdominal ultrasound and thoraco-abdominal CT scan identified a subhepatic mass, accompanied by lymphadenopathy, initially suggestive of lymphoma. Histopathological examination and immunohistochemical studies ultimately established the diagnosis of inflammatory myofibroblastic tumor. Based on this case, we discuss the differential diagnosis and specific histopathological features associated with this rare colonic localization.
Fields of Study & Subjects
IgG4-Related and Inflammatory Diseases
Soft tissue tumor case studies
Gastrointestinal Tumor Research and Treatment
Publication details
- Journal / source
- Open Journal of Pediatrics
- Volume
- 16
- Issue
- 02
- Pages
- 242–250
- Publication date
- 1 January 2026
- Language
- EN