Outcomes of intraprocedural haemodynamic changes in patients undergoing mitral transcatheter edge-to-edge repair

EuroIntervention 2026 Open access

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Authors: Shingo Kuwata, Masaki Izumo, Tetsu Tanaka, Taishi Okuno, Yoshihiro J. Akashi, Masanori Yamamoto, Tetsuro Shimura, Atsushi Sugiura, Shunsuke Kubo, Mike Saji, Yuki Izumi, Yusuke Enta
+17 more Shinichi Shirai, Shingo Mizuno, Yusuke Watanabe, Makoto Amaki, Kazuhisa Kodama, Junichi Yamaguchi, Toru Naganuma, Hiroki Bota, Yohei Ohno, Masahiko Asami, Daisuke Hachinohe, Masahiro Yamawaki, Hiroshi Ueno, Gaku Nakazawa, Toshiaki Otsuka, Kentaro Hayashida, on behalf the OCEAN-Mitral investigators
DOI: 10.4244/eij-d-26-00084
Cited by: 1
References: 18

Abstract

BACKGROUND: While the mean left atrial pressure (mLAP) reduction during mitral transcatheter edge-to-edge repair (M-TEER) has been suggested as a potential prognostic marker, comprehensive evidence from large-scale, real-world cohorts is limited, especially with stratification by mitral regurgitation (MR) aetiology. AIMS: This study aimed to evaluate the prognostic significance of intraprocedural haemodynamic changes, particularly the mLAP reduction, during M-TEER for MR, using multicentre registry data. METHODS: From the OCEAN-Mitral registry, 2,629 patients undergoing M-TEER with intraprocedural direct mLAP measurements were included. A decrease in the mLAP was defined as follows: postprocedural mLAP-preprocedural mLAP

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Cardiac Structural Anomalies and Repair Cardiac and Coronary Surgery Techniques

Publication details

Journal / source
EuroIntervention
Publisher
Europa Digital & Publishing
Volume
22
Issue
12
Pages
e690–e700
Publication date
1 June 2026
Language
EN